WHO experts favor single-dose H1N1 vaccine regimen

first_imgOct 30, 2009 (CIDRAP News) – An expert committee that advises the World Health Organization (WHO) today updated its guidance on pandemic H1N1 vaccines, recommending a single dose for most age-groups and advising that any of the forms are safe for pregnant women.At a media briefing today, Dr Marie-Paule Kieny, director of the agency’s Initiative for Vaccine Research, said this week’s 3-day meeting of the Strategic Advisory Group of Experts (SAGE) on immunizations marked the group’s first discussion of the pandemic H1N1 vaccine since mid July, when it took up the vaccine priority question and addressed concerns about low yields with the first vaccine seed strains.”The level of evidence in October is much higher than July, and the recommendations are much more precise than July,” she said.After examining clinical trial data for all versions of the vaccine, the group recommended a single dose for everyone aged 10 and older, as long as such use in line with national regulatory authorities. Though the group said immunogenicity data are more limited for young children, it also recommended that countries that have children as a high-priority group administer one dose so that as many children can be vaccinated as possible.The United States has prioritized children to receive the pandemic vaccine has recommended that those under age 10 receive two doses. Also, Europe’s drug regulatory agency on Sep 23 announced it would stick to its initial recommendation that the three vaccines it approved be given in two doses, because data were insufficient to merit a one-dose recommendation. However, it added that one dose may be enough in adults.At a separate press briefing today, reporters asked Thomas Frieden, MD, director of the US Centers for Disease Control and Prevention (CDC), about the difference between the SAGE recommendation and the CDC’s guidance. He said preliminary vaccine data on children have not shown the desired immune response in children that would warrant a single-dose recommendation. Though the CDC is anticipating new data soon from the National Institutes of Health, “for the time being, we’re sticking with what the ACIP [Advisory Committee on Immunization Practices] has recommended,” Frieden said.Kieny said the WHO group advised that more studies are needed to guide a recommended vaccine dose for immunocompromised patients.Fourteen countries have now launched pandemic H1N1 vaccination programs, she said. In its review of early vaccine monitoring data for the pandemic, SAGE found no indication of unusual reactions, and it found that the events reported so far are well within the range of those seen with seasonal flu vaccines.Given concerns about vaccinating pregnant women, the WHO panel looked at animal studies of all forms of the vaccine and found no evidence of direct or indirect harm to fertility, pregnancy, embryonic or fetal development, birthing, or postnatal development. Given the high risk of flu complications in pregnant women, the group said any licensed vaccine can be used in pregnant women, unless specific contraindications have been outlined by national regulatory bodies.The United States is among countries where authorities have recommended that pregnant women not receive the intranasal, live attenuated H1N1 vaccine (LAIV). Public health officials were in a difficult position when the first pandemic vaccine doses were delivered, because nearly all of them were the LAIV version, though pregnant women are at the front of the line to be vaccinated. However, US officials have recently said the injectable version that pregnant women and other high-risk groups can receive makes up half of the increasing supply.The group also took up the issue of whether seasonal and pandemic H1N1 vaccines can be given at the same time. In a statement today, the WHO panel said clinical trials on coadministration of the vaccines are ongoing, but it endorsed the CDC recommendation that the intranasal versions of the seasonal and pandemic vaccines should not be given together. The group said the seasonal and pandemic vaccines can be given at the same time provided both are inactivated (injectable) or one is inactivated and the other is LAIV.Regarding options for the Southern Hemisphere’s 2009-2010 seasonal flu vaccine, SAGE weighed whether a trivalent vaccine (pandemic H1N1 plus seasonal H3N2 and B) or a bivalent vaccine (seasonal H3N2 and B) plus a separate pandemic H1N1 vaccine would be best. They concluded that both formulation options should be available, depending on national needs.See also:Oct 30 WHO statement on SAGE recommendationshttp://www.who.int/csr/disease/swineflu/notes/briefing_20091030/en/index.htmllast_img read more

I hate to see others suffer – Kanu on Covid-19 charity drive

first_imgArsenal great Nwankwo Kanu has donated relief package to residents of his home town in Owerri as the coronavirus pandemic continues to shake the global economy. Food items, sanitisers, soaps and protective equipment were donated in Imo state’s largest city, as nearby cities will also benefit from this largesse in the coming days. Apart from that, several communities were educated on how the virus can be prevented and controlled by observing simple hygiene measures. The two-time African Player of the Year has opened up on why he is a vanguard of a philanthropic drive amid the lockdown in the eastern part of Nigeria. “I value life and more importantly I hate to see others suffer, so that was my major motivation for choosing to embark on this project,” Kanu told Goal. “This is my own little way of reaching out to the struggling families during this trying period and also to show them that my heart is always with them.Advertisement The coronavirus pandemic no doubt has left a hurtful effect on people. You will agree with me that while many have been rendered jobless, many find it very difficult to feed themselves. “So far, we have visited several communities to share food items and relief materials. God helping me and with the support of Nigerians, I hope to do more because I find joy putting smiles of people’s faces. “Alongside my team, we have also embarked on sensitization walks in both urban and rural areas for them to know that coronavirus is very real while demonstrating to them how to keep a healthy lifestyle as it concerns handwashing with soap and water. I believe we can limit the spread of the virus.” Since launching the Kanu Heart Foundation (KHF) in 2000, the foundation has saved the lives of more than 560 Nigerian children. read also:Sevilla confirm Uchenna Kanu’s exit 2020 marks the 20th anniversary of the foundation that is working tirelessly towards opening a specialist hospital in Abuja, but the outbreak of Covid-19 seems to have unsettled concluded plans to play a football game, have a dinner and a concert to raise funds. Even at that, the former Super Eagles captain claimed a statement will be released as soon as a decision is taken on the next line of action. FacebookTwitterWhatsAppEmail分享 center_img Loading…last_img read more

No new cases reported locally

first_imgStatewide—The Indiana State Department of Health has reported that 481 additional Hoosiers have been diagnosed with COVID-19 today.  A total of 28,705 Indiana residents have tested positive for the coronavirus.  To date, 189,330  tests have been reported to ISDH at a 15.2% positive rate and 57 new deaths were reported for a total of 1,678 Hoosiers have died to date.Locally, no new cases or deaths were reported.  Decatur County has a total of 220 positive cases and 31 deaths, Franklin County has 106 positive cases and 7 deaths, and Ripley County has 108 positive cases and 6 deaths according to numbers reported to the Indiana State Department of Health.last_img read more

‘ONESIE’ IS NOT AMUSED AT PRAMERICA!

first_imgHow totally embarrassing but all in a good cause!Pramerica Employees did a Onesie day in aid of the “Duchenne Muscular Dystrophy” charity”. Back Row: From Left to Right Stephen McDaid, Conal McKinney, Dan Sheerin, Barry McIntyre, David Doherty, Kevin Timoney, Donal Friel and Lorraine Gallagher.Front Row Left to Right: Shirley Boyle Mairead Doherty(Carson) Rachel Jones Evan and Ciara Colhoun. ‘ONESIE’ IS NOT AMUSED AT PRAMERICA! was last modified: May 6th, 2013 by StephenShare this:Click to share on Facebook (Opens in new window)Click to share on Twitter (Opens in new window)Click to share on LinkedIn (Opens in new window)Click to share on Reddit (Opens in new window)Click to share on Pocket (Opens in new window)Click to share on Telegram (Opens in new window)Click to share on WhatsApp (Opens in new window)Click to share on Skype (Opens in new window)Click to print (Opens in new window) Tags:charitypramericalast_img read more