S.Korea’s Celltrion to begin commercial production of COVID-19 antibody drug

first_imgSouth Korea’s Celltrion Inc will begin commercial production of its experimental treatment for COVID-19 this month, it said on Tuesday, as it pushes ahead with clinical trials of the antibody drug.The company said it planned to make a request soon to regulators for emergency use authorization of the drug, but that it would start mass production – likely to amount to around 1 million doses – before receiving that approval.The treatment became the country’s first COVID-19 antibody drug to be tested on humans after receiving regulatory approval in July for clinical trials. “We have confirmed the safety of the antiviral antibody drug in the process of the local Phase I clinical trial,” Kwon Ki-sung, head of Celltrion’s R&D unit, told Reuters.Celltrion completed a Phase I trial on 32 volunteers in the country and is enrolling an additional nine participants for another Phase I study before moving on to later stage trials, for which regulatory reviews are already underway.The company is separately conducting overseas human trials of its treatment in the United Kingdom, which will be followed by global second and third stage trials in patients with mild and moderate symptoms.Shares of Celltrion surged as much as 5.6% on Tuesday, while the broader KOSPI gained 0.7%.Other companies developing potential COVID-19 treatments include Eli Lilly and Co, Regeneron Pharmaceuticals Inc and AbbVie. Topics :last_img read more

Compromise Budget: Government That Works

first_imgLike Governor Tom Wolf on Facebook: Facebook.com/GovernorWolf December 09, 2015 By: J.J. Abbott, Deputy Press Secretary Compromise Budget: Government That Workscenter_img Government That Works,  The Blog In bipartisan fashion, the Pennsylvania Senate overwhelmingly passed a compromise budget based on the agreed-to framework established weeks ago by the Governor and legislative leaders. In addition to historic investments in our schools and the first step toward the restoration of the cuts made to human services programs, this budget enhances the governor’s mission to create a government that works for all Pennsylvanians.This compromise budget invests in important programs aimed at solving some of Pennsylvania’s biggest crises and expanding some of the commonwealth’s most successful programs: increasing funding to combat the heroin epidemic, investing in workforce development programs, funding four new cadet classes for the Pennsylvanian State Police, increasing access to food security for needy families, and protecting Pennsylvanians’ air and water.Attacking the Heroin EpidemicThe compromise budget includes an additional $9 million in funding toward efforts to combat the heroin epidemic spread across three agencies. Since his inauguration, Governor Wolf has worked with his administration to provide real solutions not only to save lives but also to help addicted individuals and their families get the treatment they need to live long, productive lives.Such actions taken by the Wolf Administration include the development of the ABC-MAP prescription drug monitoring program which can finally be implemented upon passage of the budget, the creation of the interagency Heroin Task Force, the support for the use of naloxone at schools across the commonwealth, and stocking all Pennsylvania State Police cars and Capitol Police officers with the naloxone drug. Since equipping State Police cars with naloxone, over 300 lives have been saved with this drug. Further, at the Governor’s request, Physician General Dr. Rachel Levine signed a standing-order allowing any Pennsylvanian to obtain this life-saving drug.Investing in WorkersThe budget increases funding for Department of Labor and Industry programs totaling nearly $11 million, including $4 million for increased training initiatives; $5 million to leverage an additional $18.5 million in federal funds for vocational rehabilitation and assistance; and $400,000 to expand services at centers for independent living. This infusion of state dollars will help Pennsylvania significantly strengthen and expand these vital programs and partnerships with higher education and the private sector.Making Pennsylvania SaferThe compromise budget increases funding for the Pennsylvania State Police by nearly $25 million to fund four new cadet classes and increase complement to the highest level in commonwealth history. This will increase the strength of Pennsylvania’s primary law enforcement and public safety agency despite expected retirements and turnover.Strengthening Food SecurityThe budget includes an increase in the State Food Purchase Program of $3.4 million, providing additional funding for local food banks, to ensure the most vulnerable of Pennsylvania’s families can find food security in their time of need.Protecting Air and WaterThis compromise increases funding for Department of Environmental Protection program appropriations by more than $8 million, including a nearly $5 million increase to protect Pennsylvanians’ air and water quality. SHARE Email Facebook Twitterlast_img read more

Bangladesh Takes Over Another Batch of Damen Dredgers

first_imgFollowing recent dredger deliveries in Bangladesh, and successfully organised Dredging Seminar last month in Dhaka, Damen has again delivered multiple dredgers from available stock.According to Regional Sales Director, Rabien Bahadoer, Damen has again confirmed its long-term commitment to Bangladesh by delivering quality dredgers with a proven design from ready stock.“This will swiftly help our customers to start their dredging job in supporting the riverine country.” Mr Bahadoer added “Our dedicated Service Team has overseen a very fast handover. This August delivery comes very soon after our well received Dredging Seminar in July. The dredgers include various optional items, such as production meters, spud carriage systems and spare parts. A unique achievement, and we expect that there is more to come.”Damen has had a presence in Bangladesh since the 1970s. There are quite a number of Damen vessels in operation in the country from that time of which some are still in function.last_img read more

GeoSea Nets Moray OWF East Substructures EPCI Deal

first_imgGeoSea has entered into an  engineering, procurement, construction and installation (EPCI) contract with the Moray Offshore Windfarm East (MOWE).The contract covers EPCI of around 100 wind turbine foundations and 3 offshore substation platform foundations, and the transport and installation of 3 offshore substation platforms for the wind farm.The contract award is subject to financial close which is expected to take place in the second half of 2018, GeoSea said.Moray Offshore Windfarm East is a joint venture company owned by EDP Renewables (77 %) and ENGIE (23 %).The project was recently awarded a £57.50/MWhr contract for Difference (CfD) by the UK Government.Jan Klaassen, business unit manager Offshore Renewables of Geosea: “Together with Ramboll, GeoSea has designed a jacket foundation concept integrating the challenges of the site, however optimized for fabrication and installation. The supply chain of approximately 100 steel jacket foundations and corresponding steel piles will be lined up the coming months. Moray East and GeoSea will pay high attention to maximize local (UK) content for the different types of services and suppliers, as far as reasonably possible.”Oscar Diaz, project director of Moray East: “Our close work and co-operation with suppliers like GeoSea has been vital to being able to develop a project which is capable of delivering power at less than half the price of projects under construction today. The extensive works within this package mean that the announcement of GeoSea represents major progress to project delivery. This work package can bring significant opportunities to the economy, and our ongoing work with Geosea will enable those opportunities to be optimized.”last_img read more

November Indiana Employment Report

first_imgStatewide—Indiana’s unemployment rate stands at 3.2 percent for November and remains lower than the national rate of 3.5 percent. The monthly unemployment rate is a U.S. Bureau of Labor Statistics indicator that reflects the number of unemployed people seeking employment within the prior four weeks as a percentage of the labor force.Indiana’s labor force had a net increase of 346 over the previous month. This was a result of an increase of 308 unemployed residents and an increase of 38 employed residents. Indiana’s total labor force, which includes both Hoosiers employed and those seeking employment, stands at 3.38 million, and the state’s 64.4 percent labor force participation rate remains above the national rate of 63.2 percent.last_img read more

Fernandes pens new Sporting CP deal

first_imgRelatedPosts Ighalo: My best moment as ‘Red Devil’ EPL: Crystal Palace stun sloppy Man U EPL: Red Devils attack Palace Bruno Fernandes has signed a new deal with Sporting CP.Fernandes has dealt Manchester United and Tottenham a blow by extending his contract with Sporting.The new contract sees his buyout clause rise from £65 million to £85 million.Fernandes expressed his delight at putting pen to paper on a contract extension to 2023.“It’s a pride for me and a recognition of my work; it’s a sign that I’m doing things well,” he said.“I have been trying my best to do what is best for the club. It is for what I did on the pitch, but also showed that I liked Sporting CP and took pride in representing the club I represent.“For me it is, and always will be, a privilege to be here and be able to wear the Sporting CP jersey.“You can expect more and better. I promise the same delivery and dedication so we can have more moments of glory as we had last season.”Tags: Bruno FernandesManchester UnitedSporting CPlast_img read more

Osimhen’s goal fails to rescue Lille as Marseille close Ligue 1 gap

first_imgRelatedPosts Napoli Coach: Osimhen young lad with old brain Neymar bags two-match ban Neymar, four others sent off as Marseille grab rare win at PSG Olympique de Marseille cut the lead by Paris St-Germain at the top of Ligue 1 in France to 10 points on Sunday after a 2-1 win at Lille. Two quickfire goals midway through the second half gave them the win after Nigerian international Victor Osimhen had given the hosts the lead. Champions PSG are in pole position on 62 points from 25 games after Saturday’s 4-4 draw at Amiens. Marseille have 52 points while Lille stayed fourth on 40 points after the visitors came from behind in an entertaining clash. Osimhen twice came close in the first half before he fired Lille into a 51st minute lead. He scored with a dinked shot over goalkeeper Steve Mandanda after he took a defence-splitting pass from Jonathan Bamba in his stride. Marseille missed a penalty kick on the hour as home goalkeeper Mike Maignan saved Valentin Rongier’s spot kick after Tiago Djalo tripped Bouna Sarr, but Lille’s joy was short-lived. The visitors levelled in the 67th minute as Lille defender Reinildo Mandava diverted Valerie Germain’s glancing header into his own net and the Marseille midfielder again turned provider two minutes later. Germain broke loose on the right flank and sent a superb low cross for Argentine striker Dario Benedetto to tap the ball in at the near post and complete Marseille’s fightback. Earlier on Sunday, Olympique Lyonnais continued their patchy form with a 1-1 home draw against Strasbourg after Kevin Lucien Zohi cancelled out Bertrand Traore’s opener for the home side. The result left Lyon in 11th place on 34 points while Strasbourg moved one place up to seventh on 37. Third-placed Rennes suffered a 1-0 setback at Stade Reims, while Brest stayed 13th after holding on for a 3-2 home win over struggling Saint Etienne. First half goals from Paul Lasne, Gaetan Charbonnier and Irvin Cardona gave Brest a 3-0 lead. Then the visitors, who remain hovering above the relegation zone in 16th position, set up a tense finish through Denis Bouanga and Lois Diony. Reuters/NAN.Tags: Jonathan BambaLigue 1MarseillePSGSteve MandandaVictor Osimhenlast_img read more

Ramos header puts Real Madrid back on top

first_imgSERGIO Ramos headed a late winner as Real Madrid recovered from a howler by keeper Keylor Navas to beat 10-man Real Betis to go top of La Liga.Navas escaped a red card for fouling Darko Brasanac, then spilled Antonio Sanabria’s shot into his own net.Cristiano Ronaldo headed Madrid level from a Marcelo cross before half-time.Betis defender Matteo Piccinini was sent off for dragging back Lucas Vazquez with 12 minutes left, before Ramos powered in a Toni Kroos corner.Morata cannot Bale out Madrid – but Ramos canCaptain Ramos has made a habit of scoring vital goals for Zinedine Zidane’s side this season – most notably a last-minute equaliser against Barcelona and a late winner against Deportivo, both in December.The centre-back’s power from set-pieces proved vital as Real did not quite click in attack without the suspended Gareth Bale, and with Karim Benzema named among the substitutes.Alvaro Morata, given a chance from the start, was unable to make an impact and was replaced by Benzema with 20 minutes left.Ronaldo provided his usual threat, heading a fine equaliser and seeing another goal ruled out for offside.last_img read more

Neuheisal ‘ticked off’ at Carroll over vote

first_imgWhen USC and UCLA face off at the Coliseum on Nov. 28, there will be more than a few storylines to watch.Objection · Carroll was the only Pac-10 coach to vote no. – Brandon Hui | Summer TrojanAdd one more to the list: UCLA head coach Rick Neuheisel is “ticked off” at USC’s Pete Carroll.The L.A. Times reported Tuesday that Carroll had voted against having coaches’ children under 18 on the sidelines of Pac-10 games, making him the only voice of dissent in a 9-1 vote.This apparently upset Neuheisel, who has three sons between the ages of 12 and 17 that are reportedly big Bruin fans. According to the Times, he told boosters last month in Westlake Village, Calif., that he was “ticked off” at Carroll as a result. In the video — available for viewing on the UCLA YouTube channel — Neuheisel added that he hoped: “We’re gonna walk out of this room tonight, ladies and gentlemen, ticked off at Pete Carroll, ticked off at all that is ‘SC, and we’re gonna get after their ass, alright?”This may simply be a case of what’s best for each of the coaches, as Carroll’s kids — USC assistant coach Brennan, 27-year-old former Women of Troy volleyball player Jaime, and current USC undergraduate Nathan — are all over the age of 18.last_img read more

USC looks to make it three in a row against Arizona

first_imgAfter a Halloween win in the Bay over quarterback Jared Goff and the California Golden Bears, the Trojans will return home to the Coliseum to host Arizona. The Trojans are riding a two game-win streak to improve to 5-3 while the Wildcats are coming off of two straight losses, falling to 5-4.The last time these teams met, USC barely escaped a loss in Tucson, as No. 10 Arizona missed a last-second field goal that would have won the game. Since knocking off former No. 3 Utah, USC has moved up to third place in the Pac-12 South while Arizona is fifth, ahead of only Colorado.Since taking over, interim head coach Clay Helton has slowed his team down and strayed from former head coach Steve Sarkisian’s fast-paced offense. Last week against Cal, the Trojans held Goff and the Bears offense to a season-low 61 plays and will likely bring that same approach to the Coliseum on Saturday.“When you look at some of the teams that we are playing right now, these high-play teams, you’re trying to keep that ball away from them, steal a possession from them, limit a possession for them,” Helton said.The defense fell flat against Stanford, Washington and Notre Dame, but since switching to a more controlled tempo, has been unwavering against Utah and Cal. A fast-paced offense puts a lot of pressure on the defense since the offense is limiting its time of possession. Defensive coordinator Justin Wilcox said that reducing the amount of time the defense is on the field will greatly reduce the margin of error, especially against a high-scoring team like Arizona.“They are averaging over 500 yards of offense,” defensive coordinator Justin Wilcox said. “They have scored a lot of points. They have been in the 90s and 100s in the play count, so they get a lot of plays.”Arizona running back Jared Baker will try to capitalize on the defense’s Achilles heel — run game defense. Baker slowly grinds out yards on the ground and wears down defenses, something USC struggles to defend.Arizona quarterback Jerrard Randall started in place of an injured Anu Solomon, but now that Solomon is healthy again, head coach Rich Rodriguez seems to favor some variation of the two of them. Neither one has been outstanding, so as long as USC’s defense is able to stop the run game and play through the fourth quarter, the Trojans shouldn’t have a problem getting a win.“Our D-line and linebackers are playing lights-out right now,” said redshirt sophomore safety Chris Hawkins. “From here on out, we’re going to be needed a lot.”On the other side of the ball, redshirt senior quarterback Cody Kessler is coming off a game against Cal in which he did not throw a touchdown pass. Kessler has seemingly been a non-factor in USC’s past two wins but will need a big game to make up for the potential absence of his favorite target, sophomore wide receiver JuJu Smith-Schuster.“Right now you’ve got to plan for him not to be there,” Helton said of Smith-Schuster, who had surgery to repair a fracture in his hand on Monday. “We’re not going to put a kid out there who’s not ready. If he’s ready, he’s ready. If not, we’ll save him for the next game.”Like Arizona, USC relies heavily on the run game under Helton, and especially if Smith-Schuster is out, the trio of tailbacks Justin Davis, Tre Madden and Ronald Jones will need to continue to exhaust the opposing defense. They haven’t met a defense who could stop them yet, and Arizona’s vulnerability isn’t likely to either.But many USC players have said that more important than offense and defense is playing together.“He has made us a real family,” Hawkins said.Wide receiver Darreus Rogers echoed Hawkins’s thought, and added that Helton has given the Trojans something to play for.“I believe in Coach Helton — we all believe in him — and we will do whatever it takes to win for him,” Rogers said.Kickoff is set for 7:30 p.m. in the Coliseum. The game will be aired live on ESPN.last_img read more

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